Tools and resources available in the following areas:
This FIJI plugin facilitates consistently and rapidly analysis of images from the Void Spot Assay (VSA, also known as Voiding Spot on Paper, VSOP) towards the quantification of rodent voiding function, including overlapping urine spots. It packages macros for image straightening and cropping, background subtraction and thresholding, spotfinding and determination of area, volume and quantity. (Developed by the Vezina group.)
This initiative, headed by Dr. Rolf Apweiler of the PANDA group at the EBI and Prof. Peter Scambler of the Institute of Child Health, UCL, aims to provide a unique public resource for renal research by generating high-quality, detailed functional GO annotation for mammalian gene products implicated in renal development and disease.
A description of the scientific areas in which NIDDK funds research on kidney disease
The kidney and urologic diseases clearinghouse provides comprehensive information about bladder and renal health and disease for the public. NKUDIC is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH.
It contains links to:
- NKUDIC - Kidney & Urologic Diseases
This presents and A to Z list of topics and titles of kidney and urologic diseases.
Links to statistics on kidney & urologic diseases in U.S. populations.
- National Kidney Disease Education Program (NKDEP)
An initiative of the NIDDK to learn more about kidney disease.
The National Kidney Foundation, Inc (NKF)., is the major voluntary health organization dedicated to preventing kidney disease, improving the health and well-being of individuals and families affected by kidney disease and increasing the availability of all organs for transplantation.
The NKF is the national charity in the United Kingdom Run by Kidney Patients for Kidney Patients.
The Federation’s aim throughout the UK is to promote both the best renal medical practice and treatment, and the health of persons suffering from Chronic Kidney Disease (CKD) or Established Renal Failure (ERF).
The NKF also supports the related needs of those relatives and friends who care for kidney patients.
The PKD Foundation is an organization dedicated to fighting polycystic kidney disease (PKD). The mission of the PKD Foundation is to: "Promote programs of research, advocacy, education, support and awareness in order to discover treatments and a cure for Polycystic Kidney Disease and improve the lives of all it affects."
GenePaint is a digital atlas of gene expression patterns in the mouse.
EMAGE is a free database of 2D and 3D gene expression patterns during mouse embryo development. All EMAGE data is housed in the common framework of the EMAP 3D Digital Atlas.
EMAGE aims to:
- Provide a focal point for biomedical and clinical researchers to access mouse embryo in situ gene expression data sourced from the community.
- Offer high-quality curation and annotation of this data in the spatio-temporal and anatomical framework of the EMAP Digital Atlas.
- Generate and offer methods for analysis of this data.
- Provide EMAGE in the broader context of other bioinformatics resources to generate a tool for understanding the genetic control of mouse development.
EMAGE also contains the eHistology resource, developed in collaboration with Academic Press/Elsevier, which allows interactive exploration of cellular-resolution colour images detailing mouse development with annotations from the Kaufman "Atlas of Mouse Development".
GEO is a gene expression/molecular abundance repository supporting MIAME-compliant data submissions and a curated, online resource for gene expression data browsing, query and retrieval.
Eurexpress is a transcriptome atlas database for the mouse embryo.
The Gene Expression Database (GXD) is a community resource for gene expression information from the laboratory mouse. GXD stores and integrates different types of expression data and makes these data freely available in formats appropriate for comprehensive analysis. There is particular emphasis on endogenous gene expression during mouse development.
ToppGene Suite at Cincinnati Children's Hospital Medical Center
A one-stop portal for gene list enrichment analysis and candidate gene prioritization based on functional annotations and protein interaction networks.
From the Epithelial Systems Biology Laboratory (ESBL).
From Epithelial Systems Biology Laboratory (ESBL).