What is the expression profile of a particular gene?
You can use GUDMAP to find the gene expression profile of a gene. On this page, we’ll answer the following question:
What is the gene expression profile of Slc22a3 (solute carrier family 22) in the developing reproductive system of the mouse?
On this page:
- Step 1: Search by gene
- Step 2: See if array data is available for that gene
- Step 3: Review the heatmaps in the “Array Data” section on the Gene page
Step 1: Search by gene
On the home page of www.gudmap.org, use the search box, making sure the “GENE” radio button is selected, and enter the desired NCBI gene symbol, in this case “Slc22a3”.
If you’re not sure of the NCBI gene symbol, we also include most common synonyms in our gene search.
Or go to BROWSE DATA > Gene in the menu bar at the top of any page and enter “Slc22a3”
In the results, you’ll see various options for “Slc22a3” - including gene symbols that contain the string “Slc22a3” (e.g., Slc22a30).
To narrow your results, use the filtering sidebar. Below you’ll see what happens when you filter by Species.
Step 2: See if array data is available for that gene
In the “Slc22a3” row, when you look in the “Available Expression Data” column, you will see that there is array data available.
Click the “View” icon for that row to go to the Gene page for Slc22a3.
The following is a screenshot of the “Slc22a3” gene record page:
Step 3: Review the heatmaps in the “Array Data” section on the Gene page
On the gene record page, scroll down to the “Array Data” section and you’ll see several heatmaps available by region.
We recommend clicking the “Microarray Data (full screen)” to view the heatmaps at full size.
Look for the heatmap titled “Reproductive Gonadal”, then hover over the bars to see the titles which describe the tissue sample by age stage and region (which are also available in the verticle lines of text below each rectangle).
- Red indicates more expression.
- Blue indicates less expression.