Funding period: 2021 through 2026 (RFA-DK-20-013)
The goal of this phase of GUDMAP is to establish a comprehensive understanding of kidney and lower urinary tract development and maturation to inform the study of tissue maturation and aging, organ dysgenesis and disease, and ultimately organ repair and regeneration.
- Creating high-resolution multi-omics molecular atlases for developing urogenital organs (Feng Chen, Washington University, St. Louis)
- Diversification of cell types during male and female external genital development (Marty Cohn, University of Florida)
- Building a multi-scale vascular atlas of the mouse lower urinary tract (Janet R. Keast, University of Melbourne)
- High resolution transcriptome and gene regulatory mapping of human ureter and bladder across the lifespan (Byron H. Lee, Cleveland Clinic Lerner COM-CWRU)
- Regulation of prostate organogenesis by tissue-resident macrophages (Maho Shibata, The George Washington University)
- The single and same cell 3D atlas of epigenome and transcriptome of the lower urinary tract (Xue Sean Li, Cedars-Sinai Medical Center)