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GUDMAP Home

GUDMAP Disease Database

About GUDMAP Disease
The GUDMAP Disease Database uses disease terms obtained from OMIM. In total 880 OMIM Disease terms are contained within the database.

Method - determining disease/gene associations
Disease terms were obtained by querying OMIM searching for the terms "genitourinary" OR "GU" OR "renal" within the Clinical Synopsis field of the OMIM entry. The search was restricted to entries with either the #(pound), %(percent) or 'none' prefix. These three properties ensure that only entries that describe phenotypes are returned (avoiding gene entries). In order to obtain associations between these OMIM disease terms and genes the query was run with an additional text search for the gene symbol within the main text of the OMIM entry.

As a consequence some gene symbols, such as 'T' and 'Ar' produced a large number of associations with OMIM entries, the majority of which may be spurious. Please note this when inspecting results. For example, a search for the gene 'T' will bring back associations with 119 different diseases, many of these association could be spurious given that the text string 'T' is likely to appear often in the main text of the OMIM entry.

Also note that the associations between genes and diseases some associations may not necessarily be positive - e.g. a gene and a disease could be associated because it is known that the gene does not play any role in disease (e.g. Adams-Oliver Syndrome and Msx1). It is important therefore to follow the link to OMIM to confirm the nature of the association.

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Querying the GUDMAP Disease Database

To search for genes associated with a genitourinary disease:

Select the genitourinary disease that you are interested in from the pull-down menu. Then click 'Search'. The query will bring back all genes that have in-situ data in GUDMAP gene expression database that are associated with the disease chosen.

DISEASE:

Select Disease... 3-@METHYLGLUTACONIC ACIDURIA, TYPE IV 3-@METHYLGLUTACONIC ACIDURIA, TYPE V ACROCALLOSAL SYNDROME ACROFACIAL DYSOSTOSIS 1, NAGER TYPE ACTION MYOCLONUS-RENAL FAILURE SYNDROME ADAMS-OLIVER SYNDROME ADRENAL HYPERPLASIA, CONGENITAL, DUE TO 17-AL..... ADRENAL HYPOPLASIA, CONGENITAL ADRENOLEUKODYSTROPHY AGONADISM, XY, WITH MENTAL RETARDATION, SHORT..... ALAGILLE SYNDROME 1 ALPHA-THALASSEMIA/MENTAL RETARDATION SYNDROME..... ALPHA-THALASSEMIA/MENTAL RETARDATION SYNDROME..... ALPORT SYNDROME, AUTOSOMAL DOMINANT ALPORT SYNDROME, AUTOSOMAL RECESSIVE ALPORT SYNDROME, X-LINKED ALSTROM SYNDROME AMELOGENESIS IMPERFECTA, HYPOPLASTIC TYPE, IG ANDROGEN INSENSITIVITY SYNDROME ANTLEY-BIXLER SYNDROME APERT SYNDROME ARTHROGRYPOSIS, DISTAL, TYPE 2A ATAXIA-TELANGIECTASIA AUTOIMMUNE POLYENDOCRINE SYNDROME, TYPE I BARDET-BIEDL SYNDROME BARE LYMPHOCYTE SYNDROME, TYPE II BASAL CELL NEVUS SYNDROME BECKWITH-WIEDEMANN SYNDROME BEHCET SYNDROME BIRT-HOGG-DUBE SYNDROME BLADDER CANCER BLEPHAROPHIMOSIS, PTOSIS, AND EPICANTHUS INVE..... BLOOM SYNDROME BRACHYPHALANGY, POLYDACTYLY, AND TIBIAL APLAS..... BRANCHIOOTORENAL SYNDROME 1 CAMPOMELIA, CUMMING TYPE CAMPOMELIC DYSPLASIA CARNEVALE SYNDROME CARNITINE PALMITOYLTRANSFERASE II DEFICIENCY,..... CAT EYE SYNDROME CEREBRAL ARTERIOPATHY, AUTOSOMAL DOMINANT, WI..... CHARGE SYNDROME CHONDRODYSPLASIA PUNCTATA 1, X-LINKED RECESSIVE CHONDRODYSPLASIA PUNCTATA 2, X-LINKED DOMINANT CHONDRODYSPLASIA, ACROMESOMELIC, WITH GENITAL..... CHONDRODYSPLASIA-PSEUDOHERMAPHRODITISM SYNDROME CHROMOSOME 18q DELETION SYNDROME COENZYME Q10 DEFICIENCY COFFIN-SIRIS SYNDROME COLOBOMA-OBESITY-HYPOGENITALISM-MENTAL RETARD..... COLORECTAL CANCER COMPLEMENT FACTOR H DEFICIENCY CONGENITAL DISORDER OF GLYCOSYLATION, TYPE Ia CORNELIA DE LANGE SYNDROME 1 CORPUS CALLOSUM, AGENESIS OF, WITH ABNORMAL G..... COWDEN DISEASE CRANIOFRONTONASAL SYNDROME CRANIOLENTICULOSUTURAL DYSPLASIA CURRARINO SYNDROME CUSHING DISEASE, PITUITARY CUTIS GYRATA SYNDROME OF BEARE AND STEVENSON CYSTIC FIBROSIS CYSTIC FIBROSIS WITH HELICOBACTER PYLORI GAST..... CYSTINOSIS, NEPHROPATHIC CYSTINURIA D-BIFUNCTIONAL PROTEIN DEFICIENCY DANDY-WALKER-LIKE MALFORMATION WITH ATRIOVENT..... DENYS-DRASH SYNDROME DESMOSTEROLOSIS DIABETES INSIPIDUS, NEPHROGENIC, AUTOSOMAL DIABETES INSIPIDUS, NEPHROGENIC, X-LINKED DIABETES MELLITUS, INSULIN-DEPENDENT DIGEORGE SYNDROME DONNAI-BARROW SYNDROME DONOHUE SYNDROME DOSAGE-SENSITIVE SEX REVERSAL DUANE-RADIAL RAY SYNDROME DYSKERATOSIS CONGENITA, X-LINKED DYSTROPHIA MYOTONICA 1 EAR, PATELLA, SHORT STATURE SYNDROME EHLERS-DANLOS SYNDROME, TYPE IV, AUTOSOMAL DO..... ELLIS-VAN CREVELD SYNDROME EPIDERMOLYSIS BULLOSA WITH PYLORIC ATRESIA EPIPHYSEAL DYSPLASIA, MULTIPLE, WITH EARLY-ON..... EXFOLIATION SYNDROME FABRY DISEASE FACIOGENITAL DYSPLASIA FAMILIAL MEDITERRANEAN FEVER FAMILIAL MEDITERRANEAN FEVER, AUTOSOMAL DOMINANT FANCONI ANEMIA FATAL FAMILIAL INSOMNIA FRASIER SYNDROME GALACTOSEMIA GENITOPATELLAR SYNDROME GENITOURINARY DYSPLASIA COMPONENT OF WAGR SYN..... GITELMAN SYNDROME GLOBOZOOSPERMIA GLOMERULOPATHY WITH FIBRONECTIN DEPOSITS GLYCOGEN STORAGE DISEASE Ib GLYCOGEN STORAGE DISEASE V GONADAL AGENESIS GONADAL DYSGENESIS, XY TYPE GOODPASTURE SYNDROME GREIG CEPHALOPOLYSYNDACTYLY SYNDROME GROWTH HORMONE INSENSITIVITY SYNDROME GROWTH-MENTAL DEFICIENCY SYNDROME OF MYHRE HEMATURIA, BENIGN FAMILIAL HEMIFACIAL MICROSOMIA HERMANSKY-PUDLAK SYNDROME HERMAPHRODITISM, TRUE HOLOPROSENCEPHALY HOLOPROSENCEPHALY 3 HYDATIDIFORM MOLE HYPEROXALURIA, PRIMARY, TYPE I HYPERPROLINEMIA, TYPE I HYPERURICEMIC NEPHROPATHY, FAMILIAL JUVENILE HYPOGONADISM, ALOPECIA, DIABETES MELLITUS, ME..... HYPOPARATHYROIDISM, SENSORINEURAL DEAFNESS, A..... HYPOPHOSPHATEMIC RICKETS, X-LINKED DOMINANT HYPOTHALAMIC HAMARTOMAS HYPOTONIA-CYSTINURIA SYNDROME HYPOTRICHOSIS-LYMPHEDEMA-TELANGIECTASIA SYNDROME IgA NEPHROPATHY 1 INFERTILE MALE SYNDROME IRIS COLOBOMA WITH PTOSIS, HYPERTELORISM, AND..... JACOBSEN SYNDROME JOUBERT SYNDROME 1 JOUBERT SYNDROME 4 KABUKI SYNDROME KALLMANN SYNDROME 2 KALLMANN SYNDROME 3 KARTAGENER SYNDROME KEARNS-SAYRE SYNDROME LACRIMOAURICULODENTODIGITAL SYNDROME LACTIC ACIDOSIS, FATAL INFANTILE LEIOMYOMA, UTERINE LEIOMYOMATOSIS, ESOPHAGEAL AND VULVAL, WITH N..... LEOPARD SYNDROME 1 LEUKODYSTROPHY, ADULT-ONSET, AUTOSOMAL DOMINANT LEUKOENCEPHALOPATHY WITH VANISHING WHITE MATTER LIPODYSTROPHY, FAMILIAL PARTIAL, TYPE 2 LIPODYSTROPHY, FAMILIAL PARTIAL, TYPE 3 LIPOID CONGENITAL ADRENAL HYPERPLASIA MCKUSICK-KAUFMAN SYNDROME MECKEL SYNDROME, TYPE 1 MEDULLARY CYSTIC KIDNEY DISEASE 1 MEGACYSTIS-MICROCOLON-INTESTINAL HYPOPERISTAL..... MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS, X-L..... MENTAL RETARDATION, X-LINKED, SYNDROMIC 13 MENTAL RETARDATION, X-LINKED, SYNDROMIC, JARI..... MENTAL RETARDATION, X-LINKED, WITH CEREBELLAR..... METACHROMATIC LEUKODYSTROPHY METHYLMALONIC ACIDURIA AND HOMOCYSTINURIA, cb..... METHYLMALONIC ACIDURIA DUE TO METHYLMALONYL-C..... MICROPHTHALMIA, SYNDROMIC 2 MICROPHTHALMIA, SYNDROMIC 3 MICROPHTHALMIA, SYNDROMIC 7 MICROPHTHALMIA, SYNDROMIC 9 MILLER-DIEKER LISSENCEPHALY SYNDROME MOEBIUS SYNDROME MOWAT-WILSON SYNDROME MUCKLE-WELLS SYNDROME MULTICYSTIC RENAL DYSPLASIA, BILATERAL MULTIPLE ACYL-CoA DEHYDROGENASE DEFICIENCY MULTIPLE ENDOCRINE NEOPLASIA, TYPE IV MULTIPLE SCLEROSIS, SUSCEPTIBILITY TO MYOTUBULAR MYOPATHY 1 NAIL-PATELLA SYNDROME NEPHRONOPHTHISIS 1 NEPHRONOPHTHISIS 2 NEPHRONOPHTHISIS 3 NEPHRONOPHTHISIS 4 NEPHROSIS 1, CONGENITAL, FINNISH TYPE NEPHROTIC SYNDROME, EARLY-ONSET, WITH DIFFUSE..... NEPHROTIC SYNDROME, TYPE 3 NEUROBLASTOMA NIJMEGEN BREAKAGE SYNDROME NOONAN SYNDROME 1 OPITZ SYNDROME OSTEOGENESIS IMPERFECTA, TYPE IIB OSTEOGENESIS IMPERFECTA, TYPE VIII OSTEOGLOPHONIC DYSPLASIA OTOPALATODIGITAL SYNDROME, TYPE II OVARIAN DYSGENESIS 1 OVARIAN HYPERSTIMULATION SYNDROME PALLISTER-HALL SYNDROME PAPILLORENAL SYNDROME PARAGANGLIOMAS 4 PELVIC ORGAN PROLAPSE PEUTZ-JEGHERS SYNDROME PHEOCHROMOCYTOMA POLYCYSTIC KIDNEY DISEASE, AUTOSOMAL RECESSIVE POLYCYSTIC KIDNEYS POLYCYSTIC OVARY SYNDROME 1 POPLITEAL PTERYGIUM SYNDROME POR DEFICIENCY PORPHYRIA, ACUTE INTERMITTENT PRADER-WILLI SYNDROME PREECLAMPSIA/ECLAMPSIA 1 PREMATURE OVARIAN FAILURE 1 PROGESTERONE RESISTANCE PSEUDOHYPOALDOSTERONISM, TYPE I, AUTOSOMAL RE..... PSEUDOTRISOMY 13 SYNDROME REIFENSTEIN SYNDROME RENAL CELL CARCINOMA 1 RENAL CYSTS AND DIABETES SYNDROME RENAL DYSPLASIA, RETINAL PIGMENTARY DYSTROPHY..... RENAL HAMARTOMAS, NEPHROBLASTOMATOSIS, AND FE..... RENAL TUBULAR DYSGENESIS RHABDOMYOLYSIS, ACUTE RECURRENT RIEGER SYNDROME, TYPE 1 ROBINOW SYNDROME, AUTOSOMAL DOMINANT ROKITANSKY-KUSTER-HAUSER SYNDROME RUBINSTEIN-TAYBI SYNDROME SANDHOFF DISEASE SCHIMMELPENNING-FEUERSTEIN-MIMS SYNDROME SCHIZOPHRENIA 1 SENIOR-LOKEN SYNDROME 1 SENIOR-LOKEN SYNDROME 5 SEVERE COMBINED IMMUNODEFICIENCY WITH SENSITI..... SHORT SYNDROME SHPRINTZEN-GOLDBERG CRANIOSYNOSTOSIS SYNDROME SHWACHMAN-DIAMOND SYNDROME SILVER-RUSSELL SYNDROME SIMPSON-GOLABI-BEHMEL SYNDROME, TYPE 1 SIMPSON-GOLABI-BEHMEL SYNDROME, TYPE 2 SMITH-LEMLI-OPITZ SYNDROME SMITH-MAGENIS SYNDROME SPASTIC PARAPLEGIA 19, AUTOSOMAL DOMINANT SPASTIC PARAPLEGIA 4, AUTOSOMAL DOMINANT SPERMATOGENIC FAILURE, NONOBSTRUCTIVE, Y-LINKED SPINAL AND BULBAR MUSCULAR ATROPHY, X-LINKED 1 SPINAL MUSCULAR ATROPHY, INFANTILE X-LINKED SPINOCEREBELLAR ATAXIA 1 SPINOCEREBELLAR ATAXIA 17 SPINOCEREBELLAR ATAXIA 2 SPONDYLOCARPOTARSAL SYNOSTOSIS SYNDROME SPONDYLOEPIMETAPHYSEAL DYSPLASIA, STRUDWICK TYPE SYSTEMIC LUPUS ERYTHEMATOSUS TESTICULAR TUMORS TOWNES-BROCKS SYNDROME TRICHORHINOPHALANGEAL SYNDROME, TYPE II TRIGONOCEPHALY, NONSYNDROMIC TUBEROUS SCLEROSIS ULNAR-MAMMARY SYNDROME UROGENITAL ADYSPLASIA, HEREDITARY VATER ASSOCIATION VESICOURETERAL REFLUX 1 VON HIPPEL-LINDAU SYNDROME WAARDENBURG SYNDROME, TYPE I WAGR SYNDROME WALKER-WARBURG SYNDROME WEAVER SYNDROME WILLIAMS-BEUREN SYNDROME WILMS TUMOR 1 WILMS TUMOR 3 WILMS TUMOR 4 WILMS TUMOR 5 WISKOTT-ALDRICH SYNDROME WOLF-HIRSCHHORN SYNDROME XX MALE SYNDROME ZELLWEGER SYNDROME

To search for diseases associated with a known gene:

The pull-menu lists all genes with in-situ data with the GUDMAP gene expression database that have associations with OMIM genitourinary diseases. Select your gene of interests and click 'Search'. The query will bring back all disease that are associated with the chosen gene.

GENE:

Select Gene... Abcd1 Adora2b Afp Agt Aip Aire Alas1 Alx3 Alx4 Aqp2 Ar Arsa Barhl1 Barx1 Bax Bcl2 Bcl3 Bcl6 Bgn Birc5 Bmp4 Bmp5 Bmpr1b Brca1 C2 Cbl Cd34 Cdc5l Cdkn1b Chek2 Chrnb4 Clock Col3a1 Col4a3 Col4a5 Col5a1 Cops3 Crebbp Crem Crtap Ctcf Cxcl12 Cyp11a1 Cyp17a1 Dbp Dcn Dhcr7 Dhh Dlx2 Dr1 Eda Egf Egfr Emx2 En1 En2 Erbb2 Erg Esr1 Etfb Ets1 Fbn2 Fcgrt Fgf10 Fgf3 Fgfr2 Fhl1 Fktn Fos Foxa2 Foxc1 FoxL2 Foxp2 Fshr Gabra1 Gabrb3 Galt Gata3 Gh Gli1 Gli2 Gli3 Gopc Gpc3 Grb10 Grp Gsc Gtf2i Gtf2ird1 H19 Hdac2 Hes5 Hic1 Hmx1 Hnf1b Hnf4a Hoxb6 Hr Hspbap1 Id3 Igbp1 Igf1 Igfbp2 Inha Irf5 Irf6 Itga6 Jag1 Jarid1c Jarid1d Jun Kit Lama4 Lamc1 Ldb3 Lif Limk1 Lmnb1 Loxl1 Lrp2 M6pr Max Mbnl1 Mefv Mest Met Mga Mid1 Mitf Mnt Msx1 Myc Mycl1 Mycn Nfkb1 Nobox Nodal Nphp1 Nr0b1 Nr3c2 Nsd1 Ntrk3 Oprm1 Otx2 Pax1 Pax2 Pax3 Pax4 Pax6 Pax8 Pax9 Peg3 Pepd Pex2 Pex5 Pgf Pgr Pitx2 Pja1 Pms1 Pou6f2 Pparg Prnp Prokr2 Ptch1 Pter Rag1 Rara Rbp1 Rest Ret Rfx5 Runx2 Sall1 Scarb2 Sf1 Shh Sim1 Sim2 Six5 Six6 Slc3a1 Smad4 Smad7 Sox10 Sox18 Sox2 Sox5 Sox8 Sox9 Sp1 Sparc Spp1 Sra1 Sry Sst Star Stat4 Stat6 T Tbp Tbx1 Tbx3 Tbx4 Tbx5 Tcf4 Tert Tfam Tgfbr1 Trim32 Trps1 Twist1 U2af1 Umod Usf2 Uty Wnt4 Wt1 Xiap Xist Zfp37 Zfx Zic2

To search for all genes associated either a renal/urinary OR reproductive system phenotype:

The pull-down menu lists Mammalian Phenotypes (MP) for the Renal/Urinary System and the Reproductive System. Select the phenotype of interest and click 'Search'. The query returns a list of any genes (with in-situ data with the GUDMAP gene expression database) associated with the chosen phenotype and the genitourinary diseases associated with those genes.

PHENOTYPE:

Select Phenotype... abnormal anogenital distance abnormal branching of the mammary ductal tree abnormal bulbourethral gland morphology abnormal calyx morphology abnormal caput abnormal cauda abnormal cervical epithelium abnormal cervical squamous epithelium abnormal cervix morphology abnormal clitoris morphology abnormal coagulating gland morphology abnormal corpus abnormal corpus luteum abnormal decidualization abnormal distal convoluted tubule morphology abnormal efferent ductules of testis abnormal ejaculation abnormal endometrium morphology abnormal epididymis epithelium morphology abnormal epididymis morphology abnormal epididymis size abnormal epididymis weight abnormal estrous cycle abnormal female germ cell morphology abnormal female inguinal canal morphology abnormal female meiosis abnormal female reproductive anatomy abnormal female reproductive system physiology abnormal fertility/fecundity abnormal fertilization abnormal foreskin morphology abnormal gametes abnormal gametogenesis abnormal germ cell morphology abnormal gestational length abnormal gonad rudiment morphology abnormal gubernaculum morphology abnormal hymen development abnormal inguinal canal morphology abnormal involution of the mammary gland abnormal juxtaglomerular apparatus abnormal kidney clearance abnormal kidney collecting duct abnormal kidney cortex abnormal kidney development abnormal kidney epithelium morphology abnormal kidney excretion abnormal kidney medulla development abnormal kidney medulla morphology abnormal kidney morphology abnormal kidney organic anion excretion abnormal kidney organic cation excretion abnormal kidney papilla morphology abnormal kidney pelvis morphology abnormal kidney physiology abnormal kidney potassium excretion abnormal kidney protein excretion abnormal kidney pyramid morphology abnormal kidney size abnormal kidney sodium excretion abnormal kidney vasculature abnormal kidney weight abnormal labia majora morphology abnormal labia minora morphology abnormal labium morphology abnormal lactation abnormal Leydig cell morphology abnormal litter size abnormal loop of Henle abnormal male germ cell morphology abnormal male inguinal canal morphology abnormal male meiosis abnormal male reproductive anatomy abnormal male reproductive system physiology abnormal mammary gland development abnormal mammary gland embryonic development abnormal mammary gland growth during lactation abnormal mammary gland growth during pregnancy abnormal mammary gland morphology abnormal mammary gland physiology abnormal meiosis abnormal menstrual cycle abnormal mesangial cell abnormal milk composition abnormal milk ejection abnormal Mullerian duct morphology abnormal myometrium morphology abnormal nephron morphology abnormal nipple morphology abnormal oocyte morphology abnormal oogenesis abnormal ovarian follicle morphology abnormal ovarian folliculogenesis abnormal ovarian secretion abnormal ovary development abnormal ovary morphology abnormal ovary physiology abnormal ovary size abnormal ovary weight abnormal oviduct environment abnormal oviduct morphology abnormal oviduct transport abnormal ovulation abnormal parturition abnormal penile erection function abnormal penis morphology abnormal perineum morphology abnormal pine bedding color after urinary excretion abnormal podocyte abnormal podocyte foot process morphology abnormal podocyte slit diaphragm morphology abnormal podocyte slit junction morphology abnormal primary sex determination abnormal primordial germ cell migration abnormal primordial germ cell morphology abnormal primordial germ cell proliferation abnormal proliferation of spermatogonia abnormal prostate epithelium morphology abnormal prostate morphology abnormal prostate physiology abnormal prostate size abnormal prostate weight abnormal proximal convoluted tubule morphology abnormal renal corpuscle morphology abnormal renal glomerular capsule abnormal renal glomerular filtration rate abnormal renal glomerulus morphology abnormal renal plasma flow rate abnormal renal sympathetic nerve activity abnormal renal tubule morphology abnormal renal vascular resistance abnormal reproductive system development abnormal reproductive system morphology abnormal reproductive system physiology abnormal scrotum morphology abnormal secondary sex determination abnormal seminal gland morphology abnormal seminal gland size abnormal seminal gland weight abnormal seminiferous epithelium morphology abnormal seminiferous tubule morphology abnormal seminiferous tubule size abnormal septation of the cloaca abnormal Sertoli cell development abnormal Sertoli cell morphology abnormal sex determination abnormal sex gland physiology abnormal sex gland secretion abnormal sexual maturation abnormal sperm motility abnormal sperm number abnormal sperm physiology abnormal spermatid morphology abnormal spermatocyte morphology abnormal spermatogenesis abnormal spermatogonia morphology abnormal spermiation abnormal spermiogenesis abnormal spontaneous abortion rate abnormal testicular physiology abnormal testicular secretion abnormal testis development abnormal testis morphology abnormal testis size abnormal testis weight abnormal ureter development abnormal ureter morphology abnormal ureter physiology abnormal ureteric bud branching morphogenesis abnormal ureteric bud morphology abnormal urethra morphology abnormal urinary bladder epithelium morphology abnormal urinary bladder morphology abnormal urinary bladder physiology abnormal urinary bladder transitional epithelium morphology abnormal urinary system development abnormal urinary system morphology abnormal urinary system physiology abnormal urination abnormal urination pattern abnormal urine calcium level abnormal urine chemistry abnormal urine color abnormal urine enzyme level abnormal urine glucose level abnormal urine osmolality abnormal urine phosphate level abnormal urine potassium level abnormal urine sodium level abnormal urothelium abnormal uterine artery morphology abnormal uterine environment abnormal uterus development abnormal uterus morphology abnormal uterus size abnormal uterus weight abnormal vagina development abnormal vagina morphology abnormal vaginal epithelium morphology abnormal vaginal opening abnormal vas deferens morphology abnormal vulva morphology abnormal Wolffian duct morphology abnormal zona pellucida absent bulbourethral gland absent coagulating gland absent corpus luteum absent efferent ductules of testis absent epididymis absent gametes absent germ cells absent hymen absent kidney absent labia majora absent labia minora absent Leydig cells absent mammary gland absent mature ovarian follicles absent oocytes absent ovarian follicles absent ovary absent oviduct absent podocyte foot process absent podocyte slit diaphragm absent podocytes absent primordial germ cells absent prostate gland absent scrotum absent seminal gland absent sexual maturation absent ureter absent urinary bladder transitional epithelium absent uterus absent vagina absent vas deferens absent zona pellucida accumulation of giant lysosomes in kidney/renal tubule cells agonadal albuminuria altered susceptibility to kidney reperfusion injury amenorrhea aminoaciduria anoperineal fistula anuria arrest of male meiosis arrest of spermatogenesis arrest of spermiogenesis asthenozoospermia azoospermia bifid kidney bifid scrotum bifid ureter bifid uterus bifid vagina blind perineal pouch blind vagina bulbourethral gland hyperplasia bulbourethral gland hypoplasia cervical atresia chordee coagulating gland hyperplasia constricted vaginal opening cortical renal glomerulopathies cryptorchism cystic bulbourethral gland decreased albumin excretion decreased compensatory renal growth decreased corpora lutea number decreased creatinine clearance decreased ductal branching in the coagulating gland decreased epididymis weight decreased germ cell number decreased kidney weight decreased litter size decreased male germ cell number decreased mature ovarian follicle number decreased microalbumin excretion decreased oocyte cell number decreased ovary weight decreased ovulation frequency decreased potassium excretion decreased primordial germ cell number decreased prostate duct number decreased prostate weight decreased protein excretion decreased renal glomerular filtration rate decreased renal glomerulus number decreased renal plasma flow rate decreased renal sympathetic nerve activity decreased renal tubule number decreased renal vascular resistance decreased seminal gland weight decreased sodium excretion decreased susceptibility to kidney reperfusion injury decreased testis weight decreased urine glucose level decreased urine osmolality decreased urine output decreased urine potassium level decreased urine sodium level decreased uterus weight delayed fertility delayed fertilization delayed kidney development delayed sexual maturation delayed vaginal opening dilated cervix dilated kidney collecting duct dilated renal glomerular capsule dilated renal tubules dilated sex gland dilated uterus distended urinary bladder duplex kidney dystocia dysuria early sexual maturation ectopic kidney enlarged clitoris enlarged epididymis enlarged foreskin enlarged kidney enlarged labia enlarged labia majora enlarged labia minora enlarged ovary enlarged prostate enlarged scrotum enlarged seminal gland enlarged seminiferous tubules enlarged testes enlarged uterus enlarged vulva epididymal cyst epididymis degeneration epididymis epithelium degeneration epididymis hypoplasia epispadias female infertility female pseudohermaphroditism fused kidneys fused podocyte foot processes fused vaginal opening genital hemorrhage globozoospermia glomerulonephritis glomerulosclerosis glutaricadicuria hematuria hemoglobinuria hemosiderinuria herniated seminal glands hydrocele hydrometrocolops hydronephrosis hydroureter hypercalciuria hyperphosphaturia hypocalciuria hypophosphaturia hypospadia impaired acrosome reaction impaired fertilization impaired granulosa cell differentiation impaired luteal cell differentiation impaired luteinization impaired ovarian folliculogenesis impaired sperm capacitation imperforate hymen incomplete emptying of bladder increased compensatory renal growth increased corpora lutea number increased creatinine clearance increased epididymis weight increased follicle recruitment increased kidney weight increased litter size increased microalbumin excretion increased ovary weight increased potassium excretion increased primordial germ cell number increased prostate weight increased protein excretion increased renal glomerular filtration rate increased renal plasma flow rate increased renal sympathetic nerve activity increased renal tubule apoptosis increased renal vascular resistance increased seminal gland weight increased susceptibility to kidney reperfusion injury increased testis weight increased urine glucose level increased urine osmolality increased urine potassium level increased urine sodium level increased uterus weight infertility inguinal cysts interlabial sulcus ketoaciduria kidney atrophy kidney calcification kidney cortex cysts kidney cysts kidney epithelium hyperplasia kidney failure kidney hemorrhage kidney inflammation kidney medulla hyperplasia kidney medulla hypoplasia kidney stones kidney vascular congestion large penis large ureter late onset of menarche lateral prostate hypoplasia Leydig cell hyperplasia Leydig cell hypoplasia long gestation period luminal epithelium of ureter hyperplasia male germ cell apoptosis male infertility male pseudohermaphroditism mammary alveolar hyperplasia mammary ductal hyperplasia mammary gland hyperplasia mammary gland hypoplasia meiotic nondisjunction during M1 phase meiotic nondisjunction during M2 phase myoglobinuria natriuresis neurogenic bladder oligozoospermia ovarian cysts ovary atrophy ovary hemorrhage ovary hyperplasia ovary hypoplasia ovary inflammation oviduct hypoplasia ovotestis pale kidney perineal fistula persistent cloaca phimosis podocyte foot process effacement polycystic kidney polyuria priapism primary sex reversal prostate epithelial hyperplasia prostate gland hyperplasia prostate gland hypoplasia prostate inflammation proteinuria pseudohermaphroditism rectoperineal fistula rectovaginal fistula reduced female fertility reduced fertility reduced male fertility renal fibrosis renal hypoplasia renal interstitial fibrosis renal necrosis renal tubular acidosis renal tubular necrosis renal/urinary system phenotype reproductive system inflammation reproductive system phenotype rudimentary ovary rudimentary oviduct rudimentary uterus rudimentary vagina scrotum hyperplasia scrotum hypoplasia secondary sex reversal seminal gland hypoplasia seminiferous tubule degeneration Sertoli cell hyperplasia Sertoli cell hypoplasia sex reversal short gestation period short perineum short ureter single kidney small clitoris small coagulating gland small epididymis small gonad small inner medullary pyramid small kidney small labia small labia majora small labia minora small ovary small penis small prostate small scrotum small seminal gland small seminiferous tubules small testis small urethra small uterus small ventral prostate small vulva splayed clitoris splayed labia majora splayed labia minora streak gonad teratozoospermia testicular atrophy testicular hyperplasia testicular hypoplasia testis inflammation thickened vaginal epithelium thin endometrium thin myometrium thin urinary bladder transitional epithelium true hermaphroditism tubular nephritis urachus ureter dilation ureter obstruction ureter stenosis ureteral reflux urethra atresia urethra stenosis urethrovaginal fistula urinary bladder diverticulum urinary bladder hypoplasia urinary bladder prolapse urinary incontinence urolithiasis uterine atresia uterine hemorrhage uterine hyperplasia uterine hypoplasia uterine prolapse uterine rupture uterus atrophy vagina atrophy vaginal cysts vaginal dryness vaginal inflammation vas deferens aplasia vesicoureteral reflux vulval cysts vulval warts

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