Summary of mouse strains characterised by GUDMAP consortium

Mouse strains generated by GUDMAP consortium

Sort ID	Gene	Reporter Allele	Allele Type	Allele Verification	Allele Characterisation	Strain availability	Organ^*	Cell Type^*
1	Id3	Id3-RFP	ES cell derived	download (Zhang Lab)	download (McMahon Lab)	Jax strain 010983	Kidney	Broad expression including ureteric tree terminal branch excluding tip itself, renal cortical interstitium and renal capsule
2	Upk1b	Upk1b-RFP	ES cell derived	download (Zhang Lab)	download (McMahon Lab)	Jax strain 010984	Lower urinary tract	Urothelium of ureter and bladder
3	Klf3	Klf3-GFP-Cre-ERT2	ES cell derived	download (Zhang Lab)	download (McMahon Lab)	Jax strain 010985	Kidney, reproductive system	Collecting duct, renal interstitium. Testis, ovary.
4	Osr2	Osr2-RFP	ES cell derived	download (Zhang Lab)	download (McMahon Lab)	Jax strain 010986	Kidney, male reproductive system	Cortical renal tubule, highest in proximal segment of s-shaped body. Urethra and testis.
5	Sox18	Sox18-GFP-Cre-ERT2	ES cell derived	download (Zhang Lab)	download (McMahon Lab)	Jax strain 010987	Vasculature	Renal cortical and medullary vasculature
6	Cyp11a1	Cyp11a1-GFP-Cre	ES cell derived	download (Zhang Lab)	download (McMahon Lab)	Jax strain 010988	Male reproductive system	Leydig cell (and adrenal gland)
7	Ifitm3 (Fragilis)	Ifitm3-RFP	ES cell derived	download (Zhang Lab)	download (McMahon Lab)	Jax strain 013139	Reproductive system	Reproductive system - germ cell
8	Akr1b7	Akr1b7-TagRFP-T	BAC transgenic	download (McMahon Lab)	download (McMahon Lab)	Jax strain 013137	Kidney	Medullary vasculature
9	Upk3a	Upk3a-GFP-Cre-ERT2	BAC transgenic	download (McMahon Lab)	download (McMahon Lab)	Jax strain 015855	Lower urinary tract	Urothelium of ureter and bladder
10	Tmem100	Tmem100-GFP-Cre-ERT2	BAC transgenic	download (McMahon Lab)	download (McMahon Lab)	Jax strain 014159	Kidney, reproductive system, vasculature	Proximal renal vesicle, parietal epithelium adjacent to WT1+ve cells demarcating future podocytes of Bowmanʼs capsule. Renal cortical vasculature. Wolffian and Mullerian ducts.
11	S100b	S100b-GFP-Cre-ERT2	BAC transgenic	download (McMahon Lab)	download (McMahon Lab)	Jax strain 014160	Glial lower urinary tract	Pelvic ganglia, glial progenitors in bladder. Developing bone.
12	Uchl1	Uchl1-mCherry/GFPgpi	BAC transgenic	download (Southard-Smith Lab)	download (Southard-Smith Lab)	Jax strain 016981	Urinary system, reproductive system	Autonomic nervous system
13	Foxl2	Foxl2-GFP-Cre-ERT2	ES cell derived	download (Zhang Lab)	download (McMahon Lab)	Jax strain 015854	Female reproductive system	Ovary medulla, granulosa cell precursors
14	Cited	Cited-TagRFP-T	BAC transgenic	download (McMahon Lab)	download (McMahon Lab)	Jax strain 015853	Kidney, male reproductive system	Cap mesenchyme (reproductive system expression not characterised)
15	Tshz3	Tshz3-GC	BAC transgenic	download (McMahon Lab)	download (McMahon Lab)	Jax strain 017494	Kidney	Smooth muscle actin positive cells (some ectopic expression and some non-expressing domains in urogenital system)
16	Crim1	Crim1-GCE	ES cell derived	download (Zhang Lab)	download (McMahon Lab)	Jax strain 017495	Vasculature	Endothelial cells (subset of PDGFR-b population)
17	Lfng	Lfng-nucTagRFP-T-IRES-CE	BAC transgenic	download (McMahon Lab)	download (McMahon Lab)	Jax strain 017496	Kidney	Renal vesicle, early tubule
18	Wnt11	Wnt11-myrTagRFP-T-IRES-CE	BAC transgenic	download(McMahon Lab)	download (McMahon Lab)	Jax strain 018683	Kidney	Ureteric bud, ureteric tip, ureteric tree, developing collecting ducts, mesonephros of male and mesonephros of female
19	Meox	Meox1-nuc TagRFP-T-IRES-CE	BAC transgenic	download(McMahon Lab)	download (McMahon Lab)	Jax strain 018682	Kidney	Cap mesenchyme progenitors, renal vesicle derivatives

^* Please note that whilst expression has been analysed in other parts of the urogenital system this analysis has not been exhaustive so that other sites of expression may exist.

Mouse strains generated by external sources

Sort ID	Gene	Reporter Allele/Transgenic	Allele Type	Allele Characterisation (Potter Lab)	Strain acquired from	Organ^*	Cell Type^*
17	Hes5	Hes5-GFP	BAC transgenic	download PDF / download movie (.avi)	MMRRC	Kidney	Medial segment of s-shaped body (TS23)
18	MafB	MafB-EGFP	BAC transgenic	download PDF	MMRRC	Kidney	Visceral epithelium of glomerular tuft, synonym: podocyte layer (TS23)
19	NRP2	NRP2-EGFP	BAC transgenic	download PDF / download movie (.mov)	MMRRC	Kidney	Early proximal tubule, renal cortical interstitium (TS23)
20	Sim1	Sim1-EGFP	BAC transgenic	download PDF / download movie (.mov)	MMRRC	Kidney	Ureteric tip, ureteric tree terminal branch, cortical collecting duct, renal connecting tubule and early distal tubule (TS23)
21	Notch2	Notch2-EGFP	BAC transgenic	download PDF / download movie (.mov)	MMRRC	Kidney	Maturing renal corpuscle, s-shaped body, early proximal tubule and cortical collecting duct (TS23)
22	Irx3	Irx3-EGFP	BAC transgenic	download PDF / download movie (.mov)	MMRRC	Kidney	Renal interstitium (TS28, adult)
23	Meis1	Meis1-EGFP	BAC transgenic	download PDF / download movie (.avi)	MMRRC	Kidney	Renal cortical and medullary interstitium (TS23); glomerula and extraglomerula mesangium (TS28, adult)
24	Sema3b	Sema3b-EGFP	BAC transgenic	download PDF / download movie (.avi)	MMRRC	Kidney	Collecting duct, early tubule, late tubule (TS23)
25	Crym	Crym-EGFP	BAC transgenic	download PDF / download movie (.mov)	MMRRC	Kidney	Cap mesenchyme (TS23)

^* Please note that whilst expression has been analysed in other parts of the urogenital system this analysis has not been exhaustive so that other sites of expression may exist.

Summary of cell lines characterised by members of the GUDMAP consortium

Urogenital system cell lines funded by external sources

Sort ID	Designation	Contributor / Lab	Source Organism / Strain	Source Tissue	Cell Type	Cell Line Requests	Cell Line Data Sheet (Davies Lab)
1	6TA1	G Tai / Davies Lab	Mus musculus / H-2K^b-tsA58 ‘Immortomouse’	metanephros (11.5dpc embryonic kidney)	ureteric bud	Jamie Davies	download
2	6TA2	G Tai / Davies Lab	Mus musculus / H-2K^b-tsA58 ‘Immortomouse’	metanephros (11.5dpc embryonic kidney)	ureteric bud	Jamie Davies	download
3	6TA3	G Tai / Davies Lab	Mus musculus / H-2K^b-tsA58 ‘Immortomouse’	metanephros (11.5dpc embryonic kidney)	ureteric bud	Jamie Davies	download
4	C1A1FF	G Tai / Davies Lab	Mus musculus / H-2K^b-tsA58 ‘Immortomouse’	metanephros (11.5dpc embryonic kidney)	metanephric mesenchyme	Jamie Davies	download
5	C1B2EM	G Tai / Davies Lab	Mus musculus / H-2K^b-tsA58 ‘Immortomouse’	metanephros (11.5dpc embryonic kidney)	metanephric mesenchyme	Jamie Davies	download
6	C1B6EM	G Tai / Davies Lab	Mus musculus / H-2K^b-tsA58 ‘Immortomouse’	metanephros (11.5dpc embryonic kidney)	metanephric mesenchyme	Jamie Davies	download
7	KMMCM	G Tai / Davies Lab	Mus musculus / H-2K^b-tsA58 ‘Immortomouse’	metanephros (11.5dpc embryonic kidney)	metanephric mesenchyme	Jamie Davies	download
8	KMML1	G Tai / Davies Lab	Mus musculus / H-2K^b-tsA58 ‘Immortomouse’	metanephros (11.5dpc embryonic kidney)	metanephric mesenchyme	Jamie Davies	download
9	Six2A3	G Tai / Davies Lab	Mus musculus / H-2K^b-tsA58 ‘Immortomouse’	metanephros (11.5dpc embryonic kidney)	metanephric mesenchyme	Jamie Davies	download
10	Six4C6	G Tai / Davies Lab	Mus musculus / H-2K^b-tsA58 ‘Immortomouse’	metanephros (11.5dpc embryonic kidney)	metanephric mesenchyme	Jamie Davies	download
11	Six5N5	G Tai / Davies Lab	Mus musculus / H-2K^b-tsA58 ‘Immortomouse’	metanephros (11.5dpc embryonic kidney)	metanephric mesenchyme	Jamie Davies	download
12	Six5N6	G Tai / Davies Lab	Mus musculus / H-2K^b-tsA58 ‘Immortomouse’	metanephros (11.5dpc embryonic kidney)	metanephric mesenchyme	Jamie Davies	download


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	Contacts	Citing GUDMAP