Metanephros

Lower Urinary Tract

Early Genitourinary System

Male Reproductive System

Female Reproductive System

 

 


Tissue Summary: s-shaped body (TS21-TS27)


About

s-shaped body Description

The comma-shaped body elongates, folds and acquires an S shape. The S-shaped nephron, connected to the ureteric tip via a renal connecting tubule, has differentiated into additional molecular regions and can be further subdivided into proximal, medial and distal segments.



View s-shaped body in GUDMAP Development Tutorials


In Situ Data

Link to s-shaped body in-situ data for TS17 Link to s-shaped body in-situ data for TS18 Link to s-shaped body in-situ data for TS19 Link to s-shaped body in-situ data for TS20 Link to s-shaped body in-situ data for TS21 Link to s-shaped body in-situ data for TS22 Link to s-shaped body in-situ data for TS23 Link to s-shaped body in-situ data for TS24 Link to s-shaped body in-situ data for TS25 Link to s-shaped body in-situ data for TS26 Link to s-shaped body in-situ data for TS27 Link to s-shaped body in-situ data for TS28

Validated Anchor/Marker Genes

Anchors (0)

Anchor genes are defined as genes whose expression is restricted to one temporospatial anatomical compartment. These have been selected by microarray analyses followed by validation using section in-situ hybridisation.

Currently no defined anchor genes for this component

 

Markers (17)

Marker genes are defined as genes which display a regional or enriched expression pattern and may be useful in identifying one or more particular temporospatial compartment(s). These have been selected by microarray analyses followed by validation using section in-situ hybridisation.

Gene SymbolGene MGI IDMarker OfStageAlso Marker OfGUDMAP IDReference
Bmp2 MGI:88177 s-shaped body (EMAP:27855)
distal segment of s-shaped body (EMAP:27873)
medial segment of s-shaped body (EMAP:27879)
renal connecting tubule of s-shaped body (EMAP:27867)
TS23renal vesicle (EMAP:27831)
comma-shaped body (EMAP:27837)
early tubule (EMAP:28502)
renal connecting segment of renal vesicle (EMAP:31695)
distal renal vesicle (EMAP:31726)
GUDMAP:8949
Georgas et al. (2009)
Thiagarajan et al. (2011)
Ccnd1 MGI:88313 s-shaped body (EMAP:27855)
renal connecting tubule of s-shaped body (EMAP:27867)
distal segment of s-shaped body (EMAP:27873)
medial segment of s-shaped body (EMAP:27879)
TS23pretubular aggregate (EMAP:27745)
renal vesicle (EMAP:27831)
comma-shaped body (EMAP:27837)
early tubule (EMAP:28502)
GUDMAP:11180
Georgas et al. (2009)
Cdh4 MGI:99218 s-shaped body (EMAP:27855)
TS23pretubular aggregate (EMAP:27745)
renal vesicle (EMAP:27831)
comma-shaped body (EMAP:27837)
early tubule (EMAP:28502)
GUDMAP:7822
Georgas et al. (2009)
Cdh6 MGI:107435 s-shaped body (EMAP:27855)
medial segment of s-shaped body (EMAP:27879)
TS23renal vesicle (EMAP:27831)
comma-shaped body (EMAP:27837)
early tubule (EMAP:28502)
GUDMAP:11368
Georgas et al. (2009)
Dkk1 MGI:1329040 s-shaped body (EMAP:27855)
medial segment of s-shaped body (EMAP:27879)
TS23renal vesicle (EMAP:27831)
comma-shaped body (EMAP:27837)
early tubule (EMAP:28502)
distal renal vesicle (EMAP:31726)
GUDMAP:9045
Georgas et al. (2009)
Dll1 MGI:104659 s-shaped body (EMAP:27855)
medial segment of s-shaped body (EMAP:27879)
TS23pretubular aggregate (EMAP:27745)
renal vesicle (EMAP:27831)
comma-shaped body (EMAP:27837)
early tubule (EMAP:28502)
distal renal vesicle (EMAP:31726)
GUDMAP:11371
Georgas et al. (2009)
Greb1 MGI:2149712 s-shaped body (EMAP:27855)
medial segment of s-shaped body (EMAP:27879)
TS23pretubular aggregate (EMAP:27745)
renal vesicle (EMAP:27831)
comma-shaped body (EMAP:27837)
early tubule (EMAP:28502)
distal renal vesicle (EMAP:31726)
GUDMAP:8891
Georgas et al. (2009)
Jag1 MGI:1095416 s-shaped body (EMAP:27855)
medial segment of s-shaped body (EMAP:27879)
TS23renal vesicle (EMAP:27831)
comma-shaped body (EMAP:27837)
early tubule (EMAP:28502)
GUDMAP:8957
Georgas et al. (2009)
Lhx1 MGI:99783 s-shaped body (EMAP:27855)
medial segment of s-shaped body (EMAP:27879)
distal segment of s-shaped body (EMAP:27873)
TS23pretubular aggregate (EMAP:27745)
renal vesicle (EMAP:27831)
comma-shaped body (EMAP:27837)
early tubule (EMAP:28502)
renal connecting segment of renal vesicle (EMAP:31695)
distal renal vesicle (EMAP:31726)
GUDMAP:13416
GUDMAP:7928
GUDMAP:8211
Georgas et al. (2009)
Thiagarajan et al. (2011)
Papss2 MGI:1330223 s-shaped body (EMAP:27855)
medial segment of s-shaped body (EMAP:27879)
TS23renal vesicle (EMAP:27831)
comma-shaped body (EMAP:27837)
early tubule (EMAP:28502)
distal renal vesicle (EMAP:31726)
GUDMAP:8960
Georgas et al. (2009)
Pcsk9 MGI:2140260 s-shaped body (EMAP:27855)
medial segment of s-shaped body (EMAP:27879)
TS23renal vesicle (EMAP:27831)
comma-shaped body (EMAP:27837)
early tubule (EMAP:28502)
distal renal vesicle (EMAP:31726)
GUDMAP:8962
Georgas et al. (2009)
Pou3f3 MGI:102564 s-shaped body (EMAP:27855)
renal connecting tubule of s-shaped body (EMAP:27867)
medial segment of s-shaped body (EMAP:27879)
distal segment of s-shaped body (EMAP:27873)
TS23renal vesicle (EMAP:27831)
comma-shaped body (EMAP:27837)
early tubule (EMAP:28502)
renal connecting segment of renal vesicle (EMAP:31695)
distal renal vesicle (EMAP:31726)
GUDMAP:13707
Georgas et al. (2009)
Sox9 MGI:98371 s-shaped body (EMAP:27855)
TS23ureteric tip (EMAP:27752)
renal vesicle (EMAP:27831)
cortical renal tubule (EMAP:27999)
GUDMAP:20765
Thiagarajan et al. (2011)
Stc2 MGI:1316731 s-shaped body (EMAP:27855)
TS23capillary loop renal corpuscle (EMAP:27909)
maturing renal corpuscle (EMAP:27945)
GUDMAP:13703
Thiagarajan et al. (2011)
Tmem100 MGI:1915138 s-shaped body (EMAP:27855)
proximal segment of s-shaped body (EMAP:27885)
parietal epithelium of s-shaped body (EMAP:27903)
TS23pretubular aggregate (EMAP:27745)
renal vesicle (EMAP:27831)
comma-shaped body (EMAP:27837)
early tubule (EMAP:28502)
proximal renal vesicle (EMAP:31720)
GUDMAP:8888
GUDMAP:8886
Georgas et al. (2009)
Thiagarajan et al. (2011)
Wnt4 MGI:98957 s-shaped body (EMAP:27855)
medial segment of s-shaped body (EMAP:27879)
TS23pretubular aggregate (EMAP:27745)
renal vesicle (EMAP:27831)
comma-shaped body (EMAP:27837)
early tubule (EMAP:28502)
GUDMAP:7156
GUDMAP:8208
GUDMAP:8209
Georgas et al. (2009)
Thiagarajan et al. (2011)
Wt1 MGI:98968 s-shaped body (EMAP:27855)
proximal segment of s-shaped body (EMAP:27885)
TS23pretubular aggregate (EMAP:27745)
renal vesicle (EMAP:27831)
comma-shaped body (EMAP:27837)
early tubule (EMAP:28502)
proximal renal vesicle (EMAP:31720)
GUDMAP:8200
Georgas et al. (2009)