Metanephros

Lower Urinary Tract

Early Genitourinary System

Male Reproductive System

Female Reproductive System

 

 

Tissue Summary: renal vesicle (TS20-TS27)


About

renal vesicle description

The pretubular aggregate enlarges and begins to differentiate into the renal vesicle; an immature epithelial nephron structure with a central lumen and partial basement membrane, the first recognised structural nephron stage.
Molecular patterning divides the renal vesicle into proximal and distal regions. Late stage, more developed renal vesicles fuse with the adjacent ureteric tip via a connecting segment.



View renal vesicle in GUDMAP Development Tutorials


In Situ Data

Link to renal vesicle in-situ data for TS17 Link to renal vesicle in-situ data for TS18 Link to renal vesicle in-situ data for TS19 Link to renal vesicle in-situ data for TS20 Link to renal vesicle in-situ data for TS21 Link to renal vesicle in-situ data for TS22 Link to renal vesicle in-situ data for TS23 Link to renal vesicle in-situ data for TS24 Link to renal vesicle in-situ data for TS25 Link to renal vesicle in-situ data for TS26 Link to renal vesicle in-situ data for TS27 Link to renal vesicle in-situ data for TS28

Validated Anchor/Marker Genes

Anchors (1)

Anchor genes are defined as genes whose expression is restricted to one temporospatial anatomical compartment. These have been selected by microarray analyses followed by validation using section in-situ hybridisation.

Gene SymbolGene MGI IDAnchor OfStageAlso Marker ofGUDMAP IDReference
Npy MGI:97374 renal vesicle (EMAP:27831)
TS23comma-shaped body (EMAP:27837)
early tubule (EMAP:28502)
GUDMAP:8964
Thiagarajan et al. (2011)

 

Markers (16)

Marker genes are defined as genes which display a regional or enriched expression pattern and may be useful in identifying one or more particular temporospatial compartment(s). These have been selected by microarray analyses followed by validation using section in-situ hybridisation.

Gene SymbolGene MGI IDMarker OfStageAlso Marker OfGUDMAP IDReference
Bmp2 MGI:88177 renal vesicle (EMAP:27831)
distal renal vesicle (EMAP:31726)
renal connecting segment of renal vesicle (EMAP:31695)
TS23comma-shaped body (EMAP:27837)
s-shaped body (EMAP:27855)
renal connecting tubule of s-shaped body (EMAP:27867)
distal segment of s-shaped body (EMAP:27873)
medial segment of s-shaped body (EMAP:27879)
early tubule (EMAP:28502)
GUDMAP:8949
Georgas et al. (2009)
Thiagarajan et al. (2011)
Ccnd1 MGI:88313 renal vesicle (EMAP:27831)
TS23pretubular aggregate (EMAP:27745)
comma-shaped body (EMAP:27837)
s-shaped body (EMAP:27855)
renal connecting tubule of s-shaped body (EMAP:27867)
distal segment of s-shaped body (EMAP:27873)
medial segment of s-shaped body (EMAP:27879)
early tubule (EMAP:28502)
GUDMAP:11180
Georgas et al. (2009)
Cdh4 MGI:99218 renal vesicle (EMAP:27831)
TS23pretubular aggregate (EMAP:27745)
comma-shaped body (EMAP:27837)
s-shaped body (EMAP:27855)
early tubule (EMAP:28502)
GUDMAP:7822
Georgas et al. (2009)
Cdh6 MGI:107435 renal vesicle (EMAP:27831)
TS23comma-shaped body (EMAP:27837)
s-shaped body (EMAP:27855)
medial segment of s-shaped body (EMAP:27879)
early tubule (EMAP:28502)
GUDMAP:11368
Georgas et al. (2009)
Dkk1 MGI:1329040 renal vesicle (EMAP:27831)
distal renal vesicle (EMAP:31726)
TS23comma-shaped body (EMAP:27837)
s-shaped body (EMAP:27855)
medial segment of s-shaped body (EMAP:27879)
early tubule (EMAP:28502)
GUDMAP:9045
Georgas et al. (2009)
Dll1 MGI:104659 renal vesicle (EMAP:27831)
distal renal vesicle (EMAP:31726)
TS23pretubular aggregate (EMAP:27745)
comma-shaped body (EMAP:27837)
s-shaped body (EMAP:27855)
medial segment of s-shaped body (EMAP:27879)
early tubule (EMAP:28502)
GUDMAP:11371
Georgas et al. (2009)
Greb1 MGI:2149712 renal vesicle (EMAP:27831)
distal renal vesicle (EMAP:31726)
TS23pretubular aggregate (EMAP:27745)
comma-shaped body (EMAP:27837)
s-shaped body (EMAP:27855)
medial segment of s-shaped body (EMAP:27879)
early tubule (EMAP:28502)
GUDMAP:8891
Georgas et al. (2009)
Jag1 MGI:1095416 renal vesicle (EMAP:27831)
TS23comma-shaped body (EMAP:27837)
s-shaped body (EMAP:27855)
medial segment of s-shaped body (EMAP:27879)
early tubule (EMAP:28502)
GUDMAP:8957
Georgas et al. (2009)
Lhx1 MGI:99783 renal vesicle (EMAP:27831)
distal renal vesicle (EMAP:31726)
renal connecting segment of renal vesicle (EMAP:31695)
TS23pretubular aggregate (EMAP:27745)
comma-shaped body (EMAP:27837)
s-shaped body (EMAP:27855)
distal segment of s-shaped body (EMAP:27873)
medial segment of s-shaped body (EMAP:27879)
early tubule (EMAP:28502)
GUDMAP:13416
GUDMAP:7928
GUDMAP:8211
Georgas et al. (2009)
Thiagarajan et al. (2011)
Papss2 MGI:1330223 renal vesicle (EMAP:27831)
distal renal vesicle (EMAP:31726)
TS23comma-shaped body (EMAP:27837)
s-shaped body (EMAP:27855)
medial segment of s-shaped body (EMAP:27879)
early tubule (EMAP:28502)
GUDMAP:8960
Georgas et al. (2009)
Pcsk9 MGI:2140260 renal vesicle (EMAP:27831)
distal renal vesicle (EMAP:31726)
TS23comma-shaped body (EMAP:27837)
s-shaped body (EMAP:27855)
medial segment of s-shaped body (EMAP:27879)
early tubule (EMAP:28502)
GUDMAP:8962
Georgas et al. (2009)
Pou3f3 MGI:102564 renal vesicle (EMAP:27831)
distal renal vesicle (EMAP:31726)
renal connecting segment of renal vesicle (EMAP:31695)
TS23comma-shaped body (EMAP:27837)
s-shaped body (EMAP:27855)
renal connecting tubule of s-shaped body (EMAP:27867)
distal segment of s-shaped body (EMAP:27873)
medial segment of s-shaped body (EMAP:27879)
early tubule (EMAP:28502)
GUDMAP:13707
Georgas et al. (2009)
Sox9 MGI:98371 renal vesicle (EMAP:27831)
TS23ureteric tip (EMAP:27752)
s-shaped body (EMAP:27855)
cortical renal tubule (EMAP:27999)
GUDMAP:20765
Thiagarajan et al. (2011)
Tmem100 MGI:1915138 renal vesicle (EMAP:27831)
proximal renal vesicle (EMAP:31720)
TS23pretubular aggregate (EMAP:27745)
comma-shaped body (EMAP:27837)
s-shaped body (EMAP:27855)
proximal segment of s-shaped body (EMAP:27885)
parietal epithelium of s-shaped body (EMAP:27903)
early tubule (EMAP:28502)
GUDMAP:8888
GUDMAP:8886
Georgas et al. (2009)
Thiagarajan et al. (2011)
Wnt4 MGI:98957 renal vesicle (EMAP:27831)
TS23pretubular aggregate (EMAP:27745)
comma-shaped body (EMAP:27837)
s-shaped body (EMAP:27855)
medial segment of s-shaped body (EMAP:27879)
early tubule (EMAP:28502)
GUDMAP:7156
GUDMAP:8208
GUDMAP:8209
Georgas et al. (2009)
Thiagarajan et al. (2011)
Wt1 MGI:98968 renal vesicle (EMAP:27831)
proximal renal vesicle (EMAP:31720)
TS23pretubular aggregate (EMAP:27745)
comma-shaped body (EMAP:27837)
s-shaped body (EMAP:27855)
proximal segment of s-shaped body (EMAP:27885)
early tubule (EMAP:28502)
GUDMAP:8200
Georgas et al. (2009)

 

 

Genelists


Published Genelists

Published genelists from Microarray Analysis. Click on the number of probes to go to heatmap view


List NameDescription EntitiesGenesSubmitted ByRefs
Renal Vesicle 12.5dpcBrunskill et al.: Renal Vesicle 12.5dpc526 probesets256Bruce Aronow, Eric BrunskillBrunskill et al. (2008)
UQ Renal Vesicle E15.5Anchor genes specific to key renal compartments: Renal Vesicle E15.522 probesets15Kylie Georgas, Rathi ThiagarajanThiagarajan et al. (2011)

 



Non-Published Genelists

Non-published genelists from Microarray Analysis. Click on the list name or number of probes to go to heatmap view. Microarray Analysis Help.


List NameDescription EntitiesGenesSubmitted ByRefs
DevelopingKidney_e12.5_renal vesicle_emap-27679_100100 probesets85Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_10001000 probesets870Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_200200 probesets178Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_500500 probesets439Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k1_10013 probesets12Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k1_1000485 probesets438Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k1_20022 probesets21Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k1_500198 probesets184Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k2_1004 probesets3Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k2_100069 probesets63Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k2_20065 probesets57Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k2_500180 probesets158Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k3_10058 probesets50Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k3_1000327 probesets287Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k3_20016 probesets14Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k3_50034 probesets27Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k4_10012 probesets10Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k4_100062 probesets56Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k4_2009 probesets7Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k4_50051 probesets47Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k5_10013 probesets12Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k5_100057 probesets47Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k5_20088 probesets80Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k5_50037 probesets34Bruce Aronow
RV 110Renal Vesicle110 probesets74Bruce Aronowno ref