Metanephros

Lower Urinary Tract

Early Genitourinary System

Male Reproductive System

Female Reproductive System

 

 


Tissue Summary: stage I / stage II nephron (TS20-TS27)


About

stage I / stage II nephron description

The first two stages of nephron development.
The renal vesicle corresponds to the stage 1 nephron. The vesicle progressively elongates, forms a comma-shaped body and then an S-shaped body, corresponding to the stage 2 nephron.



View stage I / stage II nephron in GUDMAP Development Tutorials


In Situ Data

Link to stage I / stage II nephron in-situ data for TS17 Link to stage I / stage II nephron in-situ data for TS18 Link to stage I / stage II nephron in-situ data for TS19 Link to stage I / stage II nephron in-situ data for TS20 Link to stage I / stage II nephron in-situ data for TS21 Link to stage I / stage II nephron in-situ data for TS22 Link to stage I / stage II nephron in-situ data for TS23 Link to stage I / stage II nephron in-situ data for TS24 Link to stage I / stage II nephron in-situ data for TS25 Link to stage I / stage II nephron in-situ data for TS26 Link to stage I / stage II nephron in-situ data for TS27 Link to stage I / stage II nephron in-situ data for TS28

Validated Anchor/Marker Genes

Anchors (1)

Anchor genes are defined as genes whose expression is restricted to one temporospatial anatomical compartment. These have been selected by microarray analyses followed by validation using section in-situ hybridisation.

Gene SymbolGene MGI IDAnchor OfStageAlso Marker ofGUDMAP IDReference
Npy MGI:97374 renal vesicle (EMAP:27831)
comma-shaped body (EMAP:27837)
TS23early tubule (EMAP:28502)
GUDMAP:8964
Thiagarajan et al. (2011)

 

Markers (18)

Marker genes are defined as genes which display a regional or enriched expression pattern and may be useful in identifying one or more particular temporospatial compartment(s). These have been selected by microarray analyses followed by validation using section in-situ hybridisation.

Gene SymbolGene MGI IDMarker OfStageAlso Marker OfGUDMAP IDReference
Bmp2 MGI:88177 renal vesicle (EMAP:27831)
comma-shaped body (EMAP:27837)
s-shaped body (EMAP:27855)
early tubule (EMAP:28502)
distal renal vesicle (EMAP:31726)
renal connecting segment of renal vesicle (EMAP:31695)
distal segment of s-shaped body (EMAP:27873)
medial segment of s-shaped body (EMAP:27879)
renal connecting tubule of s-shaped body (EMAP:27867)
TS23GUDMAP:8949
Georgas et al. (2009)
Thiagarajan et al. (2011)
Ccnd1 MGI:88313 early tubule (EMAP:28502)
renal vesicle (EMAP:27831)
comma-shaped body (EMAP:27837)
s-shaped body (EMAP:27855)
renal connecting tubule of s-shaped body (EMAP:27867)
distal segment of s-shaped body (EMAP:27873)
medial segment of s-shaped body (EMAP:27879)
TS23pretubular aggregate (EMAP:27745)
GUDMAP:11180
Georgas et al. (2009)
Cdh4 MGI:99218 early tubule (EMAP:28502)
renal vesicle (EMAP:27831)
comma-shaped body (EMAP:27837)
s-shaped body (EMAP:27855)
TS23pretubular aggregate (EMAP:27745)
GUDMAP:7822
Georgas et al. (2009)
Cdh6 MGI:107435 early tubule (EMAP:28502)
renal vesicle (EMAP:27831)
s-shaped body (EMAP:27855)
medial segment of s-shaped body (EMAP:27879)
comma-shaped body (EMAP:27837)
TS23GUDMAP:11368
Georgas et al. (2009)
Dkk1 MGI:1329040 early tubule (EMAP:28502)
renal vesicle (EMAP:27831)
distal renal vesicle (EMAP:31726)
comma-shaped body (EMAP:27837)
s-shaped body (EMAP:27855)
medial segment of s-shaped body (EMAP:27879)
TS23GUDMAP:9045
Georgas et al. (2009)
Dll1 MGI:104659 early tubule (EMAP:28502)
renal vesicle (EMAP:27831)
distal renal vesicle (EMAP:31726)
comma-shaped body (EMAP:27837)
s-shaped body (EMAP:27855)
medial segment of s-shaped body (EMAP:27879)
TS23pretubular aggregate (EMAP:27745)
GUDMAP:11371
Georgas et al. (2009)
Greb1 MGI:2149712 early tubule (EMAP:28502)
renal vesicle (EMAP:27831)
distal renal vesicle (EMAP:31726)
comma-shaped body (EMAP:27837)
s-shaped body (EMAP:27855)
medial segment of s-shaped body (EMAP:27879)
TS23pretubular aggregate (EMAP:27745)
GUDMAP:8891
Georgas et al. (2009)
Jag1 MGI:1095416 early tubule (EMAP:28502)
renal vesicle (EMAP:27831)
comma-shaped body (EMAP:27837)
s-shaped body (EMAP:27855)
medial segment of s-shaped body (EMAP:27879)
TS23GUDMAP:8957
Georgas et al. (2009)
Lhx1 MGI:99783 renal vesicle (EMAP:27831)
comma-shaped body (EMAP:27837)
s-shaped body (EMAP:27855)
distal renal vesicle (EMAP:31726)
renal connecting segment of renal vesicle (EMAP:31695)
medial segment of s-shaped body (EMAP:27879)
distal segment of s-shaped body (EMAP:27873)
early tubule (EMAP:28502)
TS23pretubular aggregate (EMAP:27745)
GUDMAP:13416
GUDMAP:7928
GUDMAP:8211
Georgas et al. (2009)
Thiagarajan et al. (2011)
Npy MGI:97374 early tubule (EMAP:28502)
TS23renal vesicle (EMAP:27831)
comma-shaped body (EMAP:27837)
GUDMAP:8964
Georgas et al. (2009)
Papss2 MGI:1330223 early tubule (EMAP:28502)
renal vesicle (EMAP:27831)
distal renal vesicle (EMAP:31726)
comma-shaped body (EMAP:27837)
s-shaped body (EMAP:27855)
medial segment of s-shaped body (EMAP:27879)
TS23GUDMAP:8960
Georgas et al. (2009)
Pcsk9 MGI:2140260 early tubule (EMAP:28502)
renal vesicle (EMAP:27831)
distal renal vesicle (EMAP:31726)
comma-shaped body (EMAP:27837)
s-shaped body (EMAP:27855)
medial segment of s-shaped body (EMAP:27879)
TS23GUDMAP:8962
Georgas et al. (2009)
Pou3f3 MGI:102564 early tubule (EMAP:28502)
renal vesicle (EMAP:27831)
distal renal vesicle (EMAP:31726)
renal connecting segment of renal vesicle (EMAP:31695)
comma-shaped body (EMAP:27837)
s-shaped body (EMAP:27855)
renal connecting tubule of s-shaped body (EMAP:27867)
medial segment of s-shaped body (EMAP:27879)
distal segment of s-shaped body (EMAP:27873)
TS23GUDMAP:13707
Georgas et al. (2009)
Sox9 MGI:98371 renal vesicle (EMAP:27831)
s-shaped body (EMAP:27855)
TS23ureteric tip (EMAP:27752)
cortical renal tubule (EMAP:27999)
GUDMAP:20765
Thiagarajan et al. (2011)
Stc2 MGI:1316731 s-shaped body (EMAP:27855)
TS23capillary loop renal corpuscle (EMAP:27909)
maturing renal corpuscle (EMAP:27945)
GUDMAP:13703
Thiagarajan et al. (2011)
Tmem100 MGI:1915138 renal vesicle (EMAP:27831)
comma-shaped body (EMAP:27837)
s-shaped body (EMAP:27855)
early tubule (EMAP:28502)
proximal renal vesicle (EMAP:31720)
proximal segment of s-shaped body (EMAP:27885)
parietal epithelium of s-shaped body (EMAP:27903)
TS23pretubular aggregate (EMAP:27745)
GUDMAP:8888
GUDMAP:8886
Georgas et al. (2009)
Thiagarajan et al. (2011)
Wnt4 MGI:98957 renal vesicle (EMAP:27831)
comma-shaped body (EMAP:27837)
s-shaped body (EMAP:27855)
early tubule (EMAP:28502)
medial segment of s-shaped body (EMAP:27879)
TS23pretubular aggregate (EMAP:27745)
GUDMAP:7156
GUDMAP:8208
GUDMAP:8209
Georgas et al. (2009)
Thiagarajan et al. (2011)
Wt1 MGI:98968 early tubule (EMAP:28502)
renal vesicle (EMAP:27831)
proximal renal vesicle (EMAP:31720)
comma-shaped body (EMAP:27837)
s-shaped body (EMAP:27855)
proximal segment of s-shaped body (EMAP:27885)
TS23pretubular aggregate (EMAP:27745)
GUDMAP:8200
Georgas et al. (2009)

 

 

Genelists


Published Genelists

Published genelists from Microarray Analysis. Click on the number of probes to go to heatmap view


List NameDescription EntitiesGenesSubmitted ByRefs
Renal Vesicle 12.5dpcBrunskill et al.: Renal Vesicle 12.5dpc526 probesets256Bruce Aronow, Eric BrunskillBrunskill et al. (2008)
UQ Renal Vesicle E15.5Anchor genes specific to key renal compartments: Renal Vesicle E15.522 probesets15Kylie Georgas, Rathi ThiagarajanThiagarajan et al. (2011)
UQ S-Shaped Body E15.5Anchor genes specific to key renal compartments: S-Shaped Body E15.52 probesets2Kylie Georgas, Rathi ThiagarajanThiagarajan et al. (2011)
S-Shaped Body 15.5dpcBrunskill et al.: S-Shaped Body 15.5dpc642 probesets531Bruce Aronow, Eric BrunskillBrunskill et al. (2008)

 



Non-Published Genelists

Non-published genelists from Microarray Analysis. Click on the list name or number of probes to go to heatmap view. Microarray Analysis Help.


List NameDescription EntitiesGenesSubmitted ByRefs
DevelopingKidney_e12.5_renal vesicle_emap-27679_100100 probesets85Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_10001000 probesets870Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_200200 probesets178Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_500500 probesets439Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k1_10013 probesets12Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k1_1000485 probesets438Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k1_20022 probesets21Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k1_500198 probesets184Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k2_1004 probesets3Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k2_100069 probesets63Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k2_20065 probesets57Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k2_500180 probesets158Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k3_10058 probesets50Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k3_1000327 probesets287Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k3_20016 probesets14Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k3_50034 probesets27Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k4_10012 probesets10Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k4_100062 probesets56Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k4_2009 probesets7Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k4_50051 probesets47Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k5_10013 probesets12Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k5_100057 probesets47Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k5_20088 probesets80Bruce Aronow
DevelopingKidney_e12.5_renal vesicle_emap-27679_k5_50037 probesets34Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_100100 probesets87Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_10001000 probesets860Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_200200 probesets174Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_500500 probesets438Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k1_1009 probesets8Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k1_1000253 probesets224Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k1_20043 probesets40Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k1_50094 probesets82Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k2_10033 probesets28Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k2_1000215 probesets195Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k2_20033 probesets32Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k2_500123 probesets111Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k3_10023 probesets21Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k3_1000225 probesets195Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k3_20013 probesets11Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k3_50083 probesets78Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k4_10018 probesets17Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k4_1000144 probesets129Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k4_20052 probesets44Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k4_500111 probesets98Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k5_10017 probesets15Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k5_1000163 probesets157Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k5_20059 probesets50Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k5_50089 probesets81Bruce Aronow
RV 110Renal Vesicle110 probesets74Bruce Aronowno ref
SS 102S-Shaped Body102 probesets80Bruce Aronowno ref